BrainPill Review: Effective or Overrated? [2025 Pharmacist’s Take]

Also known as Citicoline, it is vital for supporting mental health, improving cognitive energy, and increasing alertness. In the brain, it is an important component in generating electrical impulses responsible for the transport of information on the neural level.

The minimum effective dose of Cognizin is 500 mg per day, and this product contains 250 mg per serving. Impressive, right?

Synapsa is a protected form of Bacopa monnieri, a relatively popular Ayurvedic herb. It is a crucial nootropic ingredient used to restore the brain and slow down cognitive decline. The usual recommended dietary intake is 300-450 mg per day, while the product contains 320 mg per serving, which is enough for a brain booster.

It is one of the most commonly used nootropic ingredients present in almost all brain boosters. It is an amino acid used to improve alertness, attention, and focus.

The product is packed with 175 mg of this amino acid, and certain studies have used 150 mg per kg of body weight in many studies [3].

It is a cognitive enhancer herb containing Huperzine A, a substance that inhibits acetylcholine activity (ACH). Acetylcholine is an enzyme that reduces the capacity of your brain. Hence, Huperzia offers you a better chance of fighting by blocking its potential.

The Brain Pill contains 5 mg of this compound per serving, which is more than enough. Let’s have a look at what the research says about the extract.

It is actually a semi-synthetic alkaloid obtained from the Vinca minor (lesser periwinkle) plant. It is known to boost the needs of the brain and provide neuroprotection. It is also used as a cognitive protective and anti-aging agent. It is known for its ability to lower blood pressure, reduce anxiety, and improve alertness.

This ingredient’s usual dietary intake is 15-60 mg per day in a divided dose with food. However, a dose of more than 10 mg per day may not be safe for pregnant women, so Brain Pill has the minimum amount of this ingredient, which is a good sign [8].

This one makes an incredible contribution to promoting microcirculation and preventing cell degeneration. In addition to regulating neurotransmitters, it also has antioxidant activity [9].

Although there is no maximum daily dose of this ingredient, it is always wise to start with a low dose. Most studies have evaluated it at 120–240 mg per day in divided doses. Brain Pill contains 100 mg per serving, which is a little underdosed but safe to use.

PS is a fatty substance whose central role in the body is to protect your brain cells. Promoting its presence can help your brain function for as long as possible.

Animal studies suggest that the level of Phosphatidylserine in the brain decreases with age, so supplementing with this substance will increase your cognition and protect your brain cells [10].

Docosahexaenoic acid is an omega-3 fatty acid that is essential for your brain to function. In fact, DHA is important because it is involved in virtually all cognitive functions and neurotransmission.

The ingredient is generally tolerated in high doses and is safe to use. However, the average daily intake is 100 mg per day [12].

It is a water-soluble vitamin that is essential for the synthesis of neurotransmitters, RNA, and DNA. Most importantly, it is useful in maintaining myelin sheaths, which are essential for neurons to function properly [13].

It is also an amino acid that improves brain function and reduces anxiety levels. It is mostly found in green tea leaves. Research indicates that it promotes relaxation without drowsiness and maintains normal sleep [14].

Also known as Pyridoxine, it plays an important role in increasing the important B vitamins dopamine and norepinephrine. It also aids in speedy recovery from depression and prevents memory loss. Research suggests that deficiency of these vitamins can lead to age-related cognitive decline [15].

Also known as vitamin B9, it’s not actually a nootropic, although it can play an important role in boosting your blood supply [16]. It can also help prevent heart disease and reduce the risk of stroke. It helps make DNA and other genetic materials.

Also known as vitamin B5, its function is to supplement the production of energy needed to maintain normal brain function. It also helps to strengthen memory by regulating the autonomic nervous system.