Supplements

In this “Supplements” category of DrugsBank, you will find only information related to dietary supplement brands. DrugsBank provides information on popular vitamins and supplements including benefits, side effects, user ratings and reviews, overdose, best places to buy, and our expert opinions.

Vitamin B12 (Vitasprint B12): Uses, Side Effects, Dosage

Cyanocobalamin (Brand Name: Vitasprint B12) and hydroxocobalamin (Brand: Redisol-H Macrabin) are complex cobalt-containing compounds present in the diet and referred to as Vitamin B12. Vitamin B12 Occurs as Water Soluble, thermostable red crystals. It is synthesized in nature only by microorganisms; Vitamin B12 is a nutrient that helps the body’s nerves and blood cells to be healthy and helps DNA to make the genetic material in all cells. Vitamin B12 also helps prevent a type of anemia called megaloblastic anemia that makes people tired and weak. It is also considered a “painkiller vitamin”. Ingredients In Vitasprint B12 Vitamin B 12…… 250 µg Glutamine… …….30 mg Phosphonoserin… 20 mg Brand Names Cyanocobalamin: Vitasprint B12 From Pfizer Hydroxycobalamin: Redisol-H Macrabin-H 500, 1000 μM; g injection. Uses of vitamin B12 (Vitasprint B12) Megadoses of vitamin B12 have been used in neuropathies, skin sarcoidosis, mental disorders and as a general tonic to relieve fatigue, improve growth. It is used in the treatment of vitamin B12 deficiency Must be given only if predisposing factors are defined for the development of a deficiency. Vitamin B12 is an effective analgesic Vitamin B12 is also important for the brain. Vitamin B12 improves sleep habits Vitamin B12 has an anti-inflammatory effect. Vitamin B12 has positive effects during pregnancy and lactation. Vitamin B12 sources (Vitasprint B12) Sources of vitamin B12 (Vitasprint B12) Kidney, liver, egg yolks, sea fish, cheese, and meat are the main ingredients of vitamin B12. The only vegetable source is legumes, which come from the microorganisms. Vitamin B12 (Vitasprint B12) Deficiency Vitamin B12 deficiency occurs for the following reasons Atrophic gastritis, in which the gastric mucosa has thinned Increased Demand During Pregnancy and Childhood. Pernicious anemia, which makes the absorption of vitamin B12 difficult Immune system disorders such as Graves’ disease or lupus Conditions that affect your small intestines, such as Crohn’s disease, celiac disease, bacterial growth or a parasite Malabsorption (damaged intestinal mucosa), intestinal resection. Mechansim Of Action of vitamin B12 (Vitasprint B12) Vitamin B12 exists in four main forms, collectively referred to as cobalamins; Deoxyadenosylcobalamin, methylcobalamin, hydroxocobalamin, and cyanocobalamin. Two of them, methylcobalamin and 5-deoxyadenosylcobalamin, are mainly used by the body. Methionine synthase requires methylcobalamin as a cofactor. This enzyme is involved in the conversion of homocysteine to an amino acid to methionine. Methionine is necessary for the methylation of DNA. 5-deoxyadenosyl cobalamin is a cofactor that converts the enzyme L-methylmalonyl-CoA succinyl-CoA. This transformation is an important step in the recovery of energy from proteins and fats. In addition, succinyl CoA is necessary for the production of hemoglobin, the substances that carry oxygen in red blood cells. Side Effects of vitamin B12 (Vitasprint B12) Even large doses of vitamin B12 are very safe.However, there are some side effects which should be taken into consideration Allergic reactions occurred during injection, probably due to contamination. Anaphylactoid reactions (probable sulfite in the formulation) occurred during intravenous injection. Nausea, vomiting, headache, dizziness, fever may occur. Involuntary or uncontrollable movements Itching Swelling Nervousness and anxiousness Dosage Orally Vitamin B12 deficiency of dietary origin, 50-150μg of Cyanocobalamin (Vitasprint B12) per day taken between meals. For the child 50-105 μg daily in 1-3 divided doses. By intramuscular injection, 1 mg of  Cyanocobalamin (Vitasprint B12) initially then repeated 10 times at intervals of 2-3 days to give 1 mg each month. Direction For Use & Dose Open the flap on the lid of the bottle. Then remove the plastic cap. The above red cap contains the active ingredient. Press this plug firmly until the white powder falls into the solution. Shake the vitasprint bottle and then Open the vial. In some very rare cases,It is possible that A small part of the plastic plug breaks and falls into the solution. Before drinking, check the solution and transfer to another glass if necessary. Pour the contents of the vial into half a glass of water or undiluted. Adults and children over the age of 12 should take the contents of a vial once a day, unless otherwise stated. Take the beverage solution prepared with water diluted or undiluted. Usual Dose is One portion Per day. Related Article: Vitamins Health Benefits And Their Deficiencies

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Vitamins Health Benefits & Their Deficiencies

1. Vitamin A Helth benefits: Essential for immune system Maintenance of normal vision and night vision Necessary for growth; induces differentiation of cells Deficiencies: Causes night blindness,xerosis,Corneal Ulcer 2. Vitamin B1 (Thiamine) Health Benefits: Vital for healthy nervous system and nerve transmission. Essential in converting glucose to energy Deficiencies: Cause koraskoff syndrome,wet beri beri,wernicke encephalopathy. 3. Vitamin B2( Riboflavin) Helth Benefits: Essential for metabolizing carbohydrates, fats, and lipids and for the degradation of fatty acids and the synthesis of ATP Acts as an intermediary in the transfer of electrons in oxidation-reduction reactions Necessary for the function of vitamins B-6, folic acid, and niacin Involved in formation of red blood cells and maintenance of body tissues, particularly the skin and eyes Deficiencies: Stomatitis ,cheilosis,seborrheic dermatitis. 4. Vitamin B3 (Niacin) Health benefits: Significant decrease in heart disease. It helps lower the level of bad cholesterol. Other health benefits of vitamin B3 include a reduction in the risk of Alzheimer’s disease, cataracts, osteoarthritis, and type-1 diabetes. It is beneficial for a healthy nervous system and a well-functioning digestive system. The minimum amount of vitamin B3 required for healthy living varies with age. Deficiencies:Pellagra(Diarrhea,dermatitis,dementia) 5. Vitamin B6  Health Benefits: Necessary for immune system function, hormone modulation, gluconeogenesis Essential in making certain amino acids and turning others into hormones Involved in metabolizing polyunsaturated fats and proteins Used to build red blood cells and maintain nerve tissue Formation of niacin Deficiencies: Cheilosis,Glossitis. 6. Vitamin B12 Health Benefits: Works with folic acid to produce red blood cells Helps build and maintain protective nerve sheaths Needed for RNA and DNA synthesis Deficiencies: Megaloblastic anemia,Pernicious Anemia 7. Vitamin C  Health Benefits: Inhibits formation of carcinogenic compounds Activates liver-detoxifying systems Enhances function of key white blood cells involved in the destruction of bacteria Antioxidant to inactivate highly reactive oxygen species; protects against damage to lipids and other molecules Protects cellular functions Protects vitamin E Integral to maintenance and building of collagen, a protein that holds the body’s cells in place Vital to bones and teeth, blood vessels, healing of wounds, and iron absorption Helps metabolize several amino acids and hormones Deficiencies:Coagulopathy,poor wound healing. 8. Folate Health benefits: Great for the Heart Promotes Sperm Viability Supports Normal Fetal Development May Reduce the Risk of Stroke Provides Neurological Support Encourages Normal Cholesterol Level Helps Perinatal Mood Management Great for Colon Health Deficiency:Megaloblastic anemia. 9. Vitamin D Health Benefits: Helps to maintain constant levels of calcium in the blood Important in insulin and prolactin secretion, muscle function, immune and stress response, melanin synthesis, and cellular differentiation Vital for kidney and parathyroid gland function Necessary for healthy bones Deficiencies: Osteomalacia in adult,Rickets in children. 10. Vitamin E Health benefits: Protects vitamin A from oxidation during digestion Enhances immune response Inhibits carcinogens from reaching target sites Can stop neurological problems associated with cystic fibrosis, liver disease early in disease process Detoxifies free radicals, prevents damage to cell membranes Prevents LDL cholesterol from turning into damaging oxidized LDL, which initiates buildup of arterial plaque which can lead to heart disease . Deficiencies: Gait disturbances,Opthalmoplegia. 11. Vitamin K Health benefits: Helps blood coagulate In conjunction with vitamins A and D helps body build bone protein Given as injection to newborns to help blood clot, sometimes to women before labor or to patients before and after surgery Deficiency: Coagulopathy.  

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