- Cancer is the second leading reason behind death and disease worldwide, accounting for almost 9 million deaths in 2015, according to the world Health Organization (WHO).In the U. S., the National Cancer Institute (NCI) estimate that almost 40 percent of U.S. men and women will have developed cancer at one point throughout their lives.The global range of latest cases of cancer are expected to grow by around 70 % within the next 20 years.
- A New study was carried out by scientists from the University of Manchester, The University of Salford in the United Kingdom and the University of Calabria in italy.It was funded by both United Kingdom universities, the Healthy Life Foundation, the Associazione Italiana per la Ricerca sul Cancro (AIRC), the European Union, and numerous private donations.
- Research Co Author professor. Michael Lisanti and colleagues explain how A combination of vitamin C and antibiotics might be key to killing cancer stem cells (Cancer stem cells are completely different from most traditional cells in that they will turn out energy from glucose through a variety of pathways. this can be one of the reasons they are able to grow and replicate better than traditional cells.)They further found that a medical care involving the antibiotic Doxycycline and ascorbic acid, or vitamin C, was up to 100 times more effective for killing cancer stem cells than 2-DG (2-Deoxyglucose), a molecule presently being tested as an anti-cancer agent in clinical trials.While Doxycycline killed several cancer cells, however others became resistant. The resistant cells were then destroyed by ascorbic acid.
- However, by following up antibiotic administration with doses of vitamin C, the researchers were conjointly able to remove glucose from Cancer Stem Cells – a “second punch” that effectively starves the cells to death.According to this research that ascorbic acid alone was up to 10 times more effective for killing CSCs than 2-DG. However, adding doxycycline to the therapy created it almost 100 times more effective.
- This isn’t the First time vitamin c has been studied to be used against cancer: it’s previously been shown to kill cancer cells within the laboratory and stop cancer growth in mice.This new two-pronged approach might prove to be helpful in eradicating cancer stem cells in humans, however strong clinical trials are necessary first as cells will behave very otherwise in a laboratory setting.Although all the medication and natural products utilized in this study are already approved to be used in humans, we do not understand surely what concentration would be required to get similar effects without being harmful.